人视网膜上皮细胞ARPE-19

细胞名称

人视网膜上皮细胞ARPE-19

货物编码

BFN60807591

产品规格

T25培养瓶x1

1.5ml冻存管x2

细胞数量

1x10^6

1x10^6

保存温度

37℃

-198℃

运输方式

常温保温运输

干冰运输

安全等级

1

用途限制

仅供科研        2类

培养体系

90%DMEM+10%FBS+1%双抗 

培养温度

37℃

二氧化碳浓度

5%

简介

人视网膜上皮细胞ARPE-19取自19岁男性。该细胞源于ATCC。

注释

Doubling time: 55 hours (from cell counting), 65 hours (from absorbance) (DOI=10.5897/IJBMBR2013.0154).

Omics: Deep proteome analysis.

Omics: Deep quantitative phosphoproteome analysis.

Omics: Metabolome analysis.

Omics: Transcriptome analysis.

Misspelling: APRE-19; Occasionally.

Derived from sampling site: Eye; retinal pigment epithelium.

基因突变

/

HLA信息

/

STR信息

Amelogenin        X,Y

CSF1PO        11

D2S1338        19

D3S1358        14,15

D5S818        13

D6S1043        17,19

D7S820        9,11

D8S1179        13

D12S391        21,22

D13S317        11,12

D16S539        9,11

D18S51        12,16

D19S433        12,13

D21S11        28,29

FGA        23

Penta D        11,13

Penta E        7,11

TH01        6,9.3

TPOX        9,11

vWA        16,19

参考文献

PubMed=27499609

Wang Y., Sang A.-M., Zhu M.-H., Zhang G.-W., Guan H.-J., Ji M., Chen H.

Tissue factor induces VEGF expression via activation of the Wnt/beta-catenin signaling pathway in ARPE-19 cells.

Mol. Vis. 22:886-897(2016)

PubMed=28978645; DOI=10.1074/jbc.M117.812677

Chiang C.-K., Tworak A., Kevany B.M., Xu B., Mayne J., Ning Z., Figeys D., Palczewski K.

Quantitative phosphoproteomics reveals involvement of multiple signaling pathways in early phagocytosis by the retinal pigmented epithelium.

J. Biol. Chem. 292:19826-19839(2017)

PubMed=29476476; DOI=10.1007/978-1-4939-7680-5_17

Fasler-Kan E., Aliu N., Wunderlich K., Ketterer S., Ruggiero S., Berger S., Meyer P.

The retinal pigment epithelial cell line (ARPE-19) displays mosaic structural chromosomal aberrations.

Methods Mol. Biol. 1745:305-314(2018)

PubMed=31254428; DOI=10.1111/ceo.13578

Churm R., Dunseath G.J., Prior S.L., Thomas R.L., Banerjee S., Owens D.R.

Development and characterization of an in vitro system of the human retina using cultured cell lines.

Clin. Exp. Ophthalmol. 47:1055-1062(2019)

PubMed=31412689; DOI=10.3390/pharmaceutics11080412

Hellinen L., Pirskanen L., Tengvall-Unadike U., Urtti A., Reinisalo M.

Retinal pigment epithelial cell line with fast differentiation and improved barrier properties.

Pharmaceutics 11:412.1-412.12(2019)